Author

Bernd Klaus

Primary ORCID profile (0000-0003-1169-1225 · 2 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

Bernd KlausiD2 papers · European Molecular Biology Laboratory

Biology Disciplines

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Bioinformatics· 1 Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Wolfgang HuberiD· 2 shared Aleksandra Pekowska· 1 shared Christophe Chabbert· 1 shared Felix Alexander Klein· 1 shared Judith Zaugg· 1 shared Lars Michael Steinmetz· 1 shared Lars Steinmetz· 1 shared Malgorzata Oles· 1 shared

Activity by Year

2014-2016 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersBioinformatics

Wolfgang HuberORCID

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Author profile →

3 papers

Recent·Most cited

Data-driven hypothesis weighting increases detection power in multiple testing

Nikolaos Ignatiadis, Bernd Klaus, Judith Zaugg, Wolfgang Huber

The paper introduces a method to improve statistical power in multiple testing by weighting hypotheses based on covariates, while controlling the false discovery rate.

Nature Methods · May 30, 2016Peer-reviewedBioinformatics

Landscape and dynamics of transcription initiation in the malaria parasite Plasmodium falciparum

Sophie Adjalley, Christophe Chabbert, Bernd Klaus, Vicent Pelechano, Lars Steinmetz

This study maps transcription start sites in Plasmodium falciparum using high-throughput sequencing, revealing TSS selection constraints and stage-specific isoform production.

bioRxiv · Aug 10, 2015Genomics

Neural lineage induction reveals multi-scale dynamics of 3D chromatin organization

Aleksandra Pekowska, Bernd Klaus, Felix Alexander Klein, Simon Anders, Malgorzata Oles, Lars Michael Steinmetz, Paul Bertone, Wolfgang Huber

The paper uses TCC sequencing to study 3D chromatin organization during neural induction in mouse cells, finding widespread changes in inter-chromosomal contacts and a role for euchromatic domains in pluripotent cells.

bioRxiv · Apr 11, 2014 · PreprintMolecular Biology