Author

Bin Xiao

Primary ORCID profile (0000-0001-9824-5695 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

Bin XiaoiD1 paper · Jiangsu Province Hospital

Biology Disciplines

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Bioinformatics· 2

Signature Assays, Organisms & Methods

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Assay:protein sequence· 2 Approach:deep learning· 1 Approach:experimental assay· 1 Approach:machine learning (classical)· 1 Research Focus:protein design· 1 Research Focus:software / tool· 1 Approach:statistical model· 1

Frequent Co-Authors

Chenjie FengiD· 2 shared Wenjia HeiD· 2 shared Aixi Bai· 1 shared Chao ZhaiD· 1 shared Feifei Hu· 1 shared Guiting Zhang· 1 shared Hao YeiD· 1 shared Jie WangiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersBioinformatics

Chenjie FengORCID

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2 papers

Recent·Most cited

Reinforcement learning with evolutionary priors unlocks multi-site enzyme optimization from sparse experimental feedback

Xiaopeng Xu, Hao Ye, Ziqi Gao, Ruochi Zhang, Xinhai Zhou, Guiting Zhang, Tao Guo, Wenjia He, Chenjie Feng, Bin Xiao, Feifei Hu, Qiangcheng Zeng, Aixi Bai, Xiao Zhang, Jie Wang, Xin Gao

AlphaVariant uses reinforcement learning with evolutionary priors to optimize enzyme variants from sparse experimental data, achieving high activity improvements in multiple rounds of optimization.

bioRxiv · Oct 21, 2026 · PreprintBioinformatics

ProteinMCP: An Agentic AI Framework for Autonomous Protein Engineering

Xiaopeng Xu, Chenjie Feng, Chao Zha, Wenjia He, Maolin He, Bin Xiao, X.-J. Gao

ProteinMCP accelerates and democratizes protein engineering by automating workflows and integrating 38 tools, achieving a comprehensive fitness modeling task in 11 minutes.

Protein Science · Mar 25, 2026Peer-reviewedBioinformatics