Author

Brian Chang

California Institute of Technology

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Approach:deep learning· 1 Research Focus:ecology & biodiversity· 1 Research Focus:host-pathogen & immune response· 1 Assay:imaging· 1 Assay:metagenomics· 1 Organism:mouse· 1 Organism:plant (other)· 1

Frequent Co-Authors

Adeline M. HajjariD· 1 shared Akeem SantosiD· 1 shared Alexander Maynard· 1 shared Anne-Marie C. OverstreetiD· 1 shared Apollo StacyiD· 1 shared Brandon Bakos· 1 shared Clare L. CasteeliD· 1 shared Craig A. HodgesiD· 1 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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1 shared paperMicrobiology

Adeline M. HajjarORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Soil microbiome functions in plant-aphid dynamics are resilient to community restructuring during compost application

Mary M Dixon, Ethan J. McAnally, Brian Chang, Elias H. Bloom, Clare L. Casteel

This study shows compost application changes soil and rhizosphere microbial communities but does not affect plant resistance to aphids, highlighting the disconnect between community structure and functional outcomes.

bioRxiv · Oct 5, 2026 · PreprintMicrobiology

CFTR dysfunction in the intestinal epithelium is sufficient to promote pathogenic expansion of E. coli and enhanced barrier permeability in cystic fibrosis

Philip P. Ahern, Naseer Sangwan, Apollo Stacy, Jessica M. Snyder, Zaria Johnson, M. Cua, Brian Chang, Alexander Maynard, Lauren Smith, Filip Sagl, Brandon Bakos, Akeem Santos, Tina Nunn, Anne-Marie C. Overstreet, Michael J. Wannemuehler, , Adeline M. Hajjar

This study shows that CFTR dysfunction in intestinal epithelial cells promotes E. coli expansion and increased intestinal permeability in cystic fibrosis.

bioRxiv · Sep 19, 2026 · PreprintMicrobiology

DeepCell Kiosk: Scaling deep learning-enabled cellular image analysis with Kubernetes

Dylan Bannon, Erick Moen, Morgan Sarah Schwartz, Enrico Borba, Takamasa Kudo, Noah F. Greenwald, Vibha Vijayakumar, Brian Chang, Edward Pao, Erik Osterman, William Graf, David Van Valen

DeepCell Kiosk scales deep learning workflows for large imaging datasets, processing 106 images in ~5.5 hours at a low cost.

Nature Methods · Jan 1, 2021Peer-reviewedSystems Biology