Label-Free In-Line Characterization of Immune Cell Culture using Quantitative Phase Imaging
Caroline E. Serafini, Viswanath Gorti, Paloma Casteleiro Costa, Aaron D. Silva Trenkle, Bharat Kanwar, Bryan K. Wang, Brian Wicker, Linda E. Kippner, Isaac LeCompte, Rui Qi Chen, Benjamin Joffe, Ye Li, Annie C. Bowles, Jing Li, Christine E. Brown, , Francisco E. Robles
This paper introduces qOBM for non-destructive, label-free monitoring of T cell cultures, showing strong correlation with traditional assays and potential for improving cell therapy development.
npj Regenerative Medicine · Nov 27, 2025Peer-reviewedImmunology