A non-invasive approach to study localized forced in 3D epithelia
Niels Gouirand, Meti Ibrahimi, Claire Valotteau, Brice Lecouffe, André Le Bivic, Dominique Massey‐Harroche, Félix Rico, Matthias Merkel, Delphine Delacour, Elsa Bazellières
This paper introduces a non-invasive method to study localized mechanical forces in 3D epithelial tissues using elastic microbeads and shows how cytoskeletal remodeling and adhesion organization respond to mechanical perturbations.
bioRxiv · Oct 23, 2026 · PreprintCell Biology