Author

C. A. Harrison

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Biochemistry· 1

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Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Assay:structural biology· 1

Frequent Co-Authors

A. Hagg· 1 shared J. C. McCoy· 1 shared K. L. Walton· 1 shared M. Czepnik· 1 shared M. Hyvonen· 1 shared M. J. Mills· 1 shared P. Gregorevic· 1 shared R. G. Walker· 1 shared

Activity by Year

2017-2017 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

A. Hagg

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1 paper

Recent·Most cited

Molecular characterization of latent GDF8 reveals mechanisms of activation

R. G. Walker, J. C. McCoy, M. Czepnik, M. J. Mills, A. Hagg, K. L. Walton, T. Cotton, M. Hyvonen, R. T. Lee, P. Gregorevic, C. A. Harrison, T. Thompson

This study characterizes the latent and activated states of GDF8 using structural and mutagenesis analyses, revealing that latent GDF8 is spring-loaded and can be activated without proteolytic cleavage.

bioRxiv · Aug 17, 2017Biochemistry