Network models of protein phosphorylation, acetylation, and ubiquitination connect metabolic and cell signaling pathways in lung cancer
K. Ross, G. Zhang, C. Akcora, Y. Lin, B. Fang, J. Koomen, E. Haura, M. Grimes
The paper uses machine learning to analyze PTM data from lung cancer cell lines, identifying functional modules and networks that reveal crosstalk between signaling pathways and metabolic processes in response to TKIs.
bioRxiv · Oct 28, 2022Cancer Biology