Formation of the pyruvoyl-dependent proline reductase Prd from Clostridioides difficile requires the maturation enzyme PrdH
C. Behlendorf, M. G. Diwo, M. Neumann-Schaal, M. Fuchs, F. Faber, W. Blankenfeldt
This paper identifies PrdH as the maturation enzyme required for the formation of the pyruvoyl group in the proline reductase Prd of C. difficile, essential for proline utilization and toxin production.
bioRxiv · Dec 15, 2023 · PreprintBiochemistry