Molecular flux control encodes distinct cytoskeletal responses by specifying SRC signaling pathway usage.
A. Kerjouan, C. Boyault, C. Oddou, E. Hiriart-Bryant, A. Grichine, A. Kraut, M. Pezet, M. Balland, E. Faurobert, I. Bonnet, Y. Coute, B. Fourcade, C. Albiges-Rizo, O. Destaing
The paper uses optogenetic control of SRC kinase to show that distinct cytoskeletal responses are encoded by spatial and temporal molecular fluxes of the same signaling protein.
bioRxiv · May 25, 2019Cell Biology