Glucosylceramide depletion disrupts endolysosomal function in GBA-linked Parkinsons fibroblasts?
M. Bhardwaj, Z. Kula, Y. Weng, D. teVruchte, C. Breda, D. J. Sillence
This study shows that GlcCer depletion in GBA-PD fibroblasts disrupts endolysosomal function, with adaGlcCer reversing pH and volume changes.
bioRxiv · Nov 30, 2023 · PreprintCell Biology