Large-scale nuclear remodeling and transcriptional deregulation occur on both derivative chromosomes after Mantle cell lymphoma chromosomal translocation
F. B. Sall, A. Pichugin, O. Iarovaia, A. Barat, T. Tsfasman, C. Brossas, M.-N. Prioleau, E. V. Sheval, A. A. Zharikova, J. Lazarovici, V. Camara-Clayette, V. Ribrag, M. Lipinski, Y. Vassetzky, D. Germini
The paper investigates transcriptional deregulation and nuclear remodeling on the der11 chromosome in Mantle cell lymphoma, identifying new oncogenes and mechanisms of their activation.
bioRxiv · Dec 30, 2019 · PreprintCancer Biology