L. Duret

PRDM9 drives the location and rapid evolution of recombination hotspots in salmonids

This study identifies PRDM9's role in driving recombination hotspots in salmonids, showing rapid evolution and conservation of its function across vertebrates.

GTDrift: A resource for exploring the interplay between genetic drift, genomic and transcriptomic characteristics in eukaryotes

GTDrift provides a resource analyzing genetic drift and genomic/transcriptomic features across 1,506 eukaryotic species, including life history traits, dN/dS ratios, and processed RNA-seq data for comparative studies.

Bridging the gap between the evolutionary dynamics and the molecular mechanisms of meiosis : a model based exploration of the PRDM9 intra-genomic Red Queen

The paper develops a theoretical model to explore the evolutionary dynamics of meiotic recombination, focusing on the role of PRDM9 and its symmetric binding in driving hotspot turnover and selection pressures.

Phylogenetic comparative approach reveals evolutionary conservatism, ancestral composition, and integration of vertebrate gut microbiota

The paper extends multivariate phylogenetic models to estimate phylosymbiosis, ancestral microbiota composition, and integration in vertebrates, finding significant conservation despite host diversification.

Random genetic drift sets an upper limit on mRNA splicing accuracy in metazoans

The paper investigates the relationship between genetic drift and mRNA splicing accuracy across metazoans, finding a negative correlation between population size and splicing rates.

A ganglioside-based senescence-associated immune checkpoint

This paper identifies GD3 as a senescence-associated immune checkpoint that suppresses NK cell-mediated clearance of senescent cells, showing that targeting GD3 can enhance anti-fibrotic effects in a mouse model.

DILS : Demographic Inferences with Linked Selection by using ABC

DILS performs demographic inferences with linked selection using ABC on population genomic data, identifying models and loci associated with gene flow and population size changes.

Bedrock radioactivity influences the rate and spectrum of mutation

This study finds that higher natural radioactivity in subterranean habitats increases mutation rates and specific mutation types in waterlice.

Population genomics supports clonal reproduction and multiple gains and losses of parasitic abilities in the most devastating nematode plant pest

This study confirms clonal reproduction in Meloidogyne incognita using population genomics and shows no significant association between genetic variation and host race or geography.

Evolution of Replication Origins in Vertebrate Genomes: Rapid Turnover Despite Selective Constraints.

The paper compares replication origin maps across vertebrates to study their evolutionary dynamics and functional constraints, finding rapid turnover despite some genetic constraints.

Codon usage bias in animals: disentangling the effects of natural selection, effective population size and GC-biased gene conversion

This study investigates codon usage bias in 31 non-model animal species, finding translational selection in large-Ne species and GC-biased gene conversion as a dominant force across all species.

Biased gene conversion drives codon usage in human and precludes selection on translation efficiency

This study shows that GC-biased gene conversion, not translation efficiency, drives codon usage variation in human genes, explaining 81.3% of the variance.

The global impact of Wolbachia on mitochondrial diversity and evolution

The paper assesses the global impact of Wolbachia on mitochondrial diversity and evolution, finding reduced polymorphism and increased substitution rates.