BiochemistrybioRxivPreprint
Protein-mediated genome folding allosterically enhances site-specific integration of foreign DNA into CRISPRs
A. Santiago-Frangos, W. S. Henriques, T. Wiegand…·B. Wiedenheft
The paper determines the structure of a CRISPR integration complex and explains how it facilitates site-specific DNA integration through DNA bending and loop formation.
DOI 10.1101/2023.05.26.542337