Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
10 papers
Recent·Most cited
T. Wiegand, J. Liu, A. W. Fritsch, L. Vogeley, I. Luvalle-Burke, J. Geisler, A. A. Hyman, S. W. Grill
The paper shows that actin polymerization counteracts N-WASP prewetting on lipid bilayers, revealing a balance between condensate formation and dissolution in cortical condensates.
bioRxiv · Apr 14, 2024Biophysics
D. Sun, X. Zhao, T. Wiegand, G. Bartolucci, C. Martin-Lemaitre, S. W. Grill, A. A. Hyman, C. Weber, A. Honigmann
The paper investigates how surface phase transitions control protein condensation to form tight junction belts through ZO-scaffold proteins and actin polymerization.
bioRxiv · Jun 24, 2023 · PreprintBiophysics
L. Emmanouilidis, E. Bartalucci, Y. Kan, M. Ijavi, M. E. Perez, P. Afanasyev, D. Boehringer, J. Zehnder, S. H. Parekh, M. Bonn, T. C. T. Michaels, T. Wiegand, F. H.- T. Allain
This study investigates FUS liquid droplet maturation, revealing a solid beta-sheet surface layer that forms during aging, with RNA inhibiting this process.
bioRxiv · Jun 2, 2023Biochemistry
A. Santiago-Frangos, W. S. Henriques, T. Wiegand, C. C. Gauvin, M. Buyukyoruk, A. B. Graham, R. A. Wilkinson, L. Triem, K. Neselu, E. T. Eng, G. C. Lander, B. Wiedenheft
The paper determines the structure of a CRISPR integration complex and explains how it facilitates site-specific DNA integration through DNA bending and loop formation.
bioRxiv · May 26, 2023 · PreprintBiochemistry
T. Wiegand, X. Wang, S. Fischer, N. J. B. Kraft, N. A. Bourg, W. Y. Brockelman, M. Cao, W. Chanthorn, C. Chu, S. Davies, S. Ediriweera, C. V. S. Gunatilleke, I. A. U. N. Gunatilleke, Z. Hao, R. Howe, , A. Huth
The paper examines latitudinal patterns in species aggregation and abundance, showing how these patterns affect coexistence in forests and introduces a framework to model their impact on extinction risk.
bioRxiv · May 18, 2023 · PreprintEcology
L. Lecoq, L. Brigandat, R. Huber, M.-L. Fogeron, M. Callon, A. Malaer, S. Wang, M. Dujardin, M. Briday, T. Wiegand, D. Durantel, D. Burdette, J.-M. Berke, B. H. Meier, M. Nassal, A. Bockmann
This study uses solid-state NMR to elucidate the molecular structure of drug-induced aberrant HBV capsid assemblies and reveals differences in capsid-RNA interactions and phosphorylation between in-cell and in vitro conditions.
bioRxiv · Sep 14, 2022Biophysics
G. Cereghetti, V. M. Kissling, L. M. Koch, A. Arm, P. Afanasyev, M. Linsenmeier, C. Eichmann, J. Zhou, Y. Cao, D. M. Pfizenmaier, S. Kroschwald, T. Wiegand, R. Cadalbert, D. Boehringer, R. Mezzenga, , M. Peter
This study identifies a conserved mechanism by which pH-sensing regions regulate reversible amyloid formation in pyruvate kinase across yeast and human cells.
bioRxiv · Mar 21, 2022 · PreprintCell Biology
J. Zehnder, R. Cadalbert, M. Yulikov, G. Kuenze, T. Wiegand
This study labels a bacterial DnaB helicase with paramagnetic probes and uses solid-state NMR to determine distance restraints and confirm its hexameric structure.
bioRxiv · Sep 14, 2021Biophysics
A. A. Malaer, N. Wili, L. A. Voelker, M. I. Kozlova, R. Cadalbert, A. Daepp, M. E. Weber, J. Zehnder, G. Jeschke, H. Eckert, A. Bockmann, D. Klose, A. Y. Mulkidjanian, B. H. Meier, T. Wiegand
The paper captures a late transition state of ATP hydrolysis in a bacterial helicase using NMR spectroscopy and identifies key interactions involving aluminum fluoride.
bioRxiv · Apr 8, 2021Biophysics
M. Calon, A. A. Malar, S. Pfister, V. Rimal, M. E. Weber, T. Wiegand, J. Zehnder, M. Chavez, R. Deb, R. Cadalbert, A. Dapp, M.-L. Fogeron, A. Hunkeler, L. Lecoq, A. Torosyan, , B. H. Meier
This paper demonstrates improved resolution in biomolecular solid-state NMR spectroscopy at 1200 MHz, showing higher peak resolution in 13C spectra and aliphatic side-chain resonances in 1H spectra compared to 850 MHz.
bioRxiv · Mar 31, 2021 · PreprintBiophysics