Failed apoptosis enhances melanoma cancer cells aggressiveness
K. Berthenet, C. Castillo Ferrer, N. Popgeorgiev, H. Hernandez-Vargas, G. Ichim
The paper shows that failed apoptosis in melanoma cells leads to increased aggressiveness through transcriptomic changes and JNK pathway activation, observed in vitro and in vivo.
bioRxiv · Sep 5, 2019Cancer Biology