The receptor binding domain of SARS-CoV-2 spike is the key target of neutralizing antibody in human polyclonal sera.
T. Steffen, E. T. Stone, M. Hassert, E. Geerling, B. T. Grimberg, A. M. Espino, P. Pantoja, C. Climent, D. F. Hoft, S. L. George, C. A. Sariol, A. K. Pinto, J. D. Brien
This study identifies the receptor binding domain (RBD) of SARS-CoV-2 spike as the primary target of neutralizing antibodies in human polyclonal sera.
bioRxiv · Aug 21, 2020 · PreprintImmunology