Th17 cells provide direct protective effects that limit stomach parasite burden following orogastric mucosal Trypanosoma cruzi infection
C. W. Cai, C. S. Eickhoff, K. A. Meza, J. R. Blase, R. E. Audette, D. H. Chan, K. A. Bockerstett, R. J. DiPaolo, D. F. Hoft
This study shows that Th17 cells protect against mucosal Trypanosoma cruzi infection by inducing NADPH oxidase activity in macrophages, reducing parasite burden in the stomach.
bioRxiv · Nov 24, 2020 · PreprintImmunology