The Cohesin ATPase cycle is mediated by specific conformational dynamics and interface plasticity of SMC1A and SMC3 ATPase domains
M. Vitoria Gomes, P. landwerlin, M.-L. Diebold-Durand, T. B. Shaik, A. Durand, E. Troesch, C. Weber, K. Brillet, M. Lemee, C. Decroos, L. Dulac, P. Antony, E. Watrin, E. Ennifar, C. Golzio, C. Romier
This study characterizes the ATPase cycle of Cohesin by showing how SMC1A and SMC3 domains undergo structural changes, revealing the role of interface plasticity in the cycle.
bioRxiv · Jun 24, 2022 · PreprintBiochemistry