Structure-based modelling and dynamics of MurM, a Streptococcus pneumoniae penicillin resistance determinant that functions at the cytoplasmic membrane interface
A. York, A. J. lloyd, C. I. del Genio, J. Shearer, K. Hinxman, K. Fritz, V. Fulop, S. Khalid, C. Dowson, D. Roper
The paper models MurM's structure and dynamics to show its interaction with phospholipids and Lipid II, revealing its role in penicillin resistance in Streptococcus pneumoniae.
bioRxiv · Jun 18, 2020Biochemistry