The role of the atypical chemokine receptor CCRL2 in myelodysplastic syndrome and secondary acute myeloid leukemia
T. KARANTANOS, P. Teodorescu, B. Perkins, I. Christodolou, C. Esteb, R. Varadhan, E. Helmenstine, T. Rajkhowa, B. Paun, C. Bonifant, W. B. Dalton, L. P. Gondek, A. R. Moliterno, M. J. Levis, G. Ghiaur, R. J. Jones
This study identifies CCRL2 as a mediator of MDS and secondary acute myeloid leukemia growth through JAK2/STAT signaling, with potential therapeutic implications.
bioRxiv · Jul 29, 2021Cancer Biology