Peptide-mimetic treatment of Pseudomonas aeruginosa in a mouse model of respiratory infection
M. G. Moule, A. B. Benjamin, M. L. Burger, C. Herlan, M. Lebedev, J. S. Lin, K. J. Koster, N. Wavare, L. G. Adams, S. Bräse, A. E. Barron, J. D. Cirillo
This study demonstrates that the peptide-mimetic TM5 effectively kills Pseudomonas aeruginosa in vitro and reduces bacterial load in a mouse model of infection with low toxicity.
bioRxiv · Oct 30, 2023 · PreprintMicrobiology