Author

C. L. Gorrie

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4

Signature Assays, Organisms & Methods

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Assay:whole-genome sequencing· 4 Approach:experimental assay· 3 Organism:bacteria (other)· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:chromatin & epigenetic regulation· 1 Approach:comparative / phylogenetic analysis· 1 Research Focus:variant calling· 1

Frequent Co-Authors

K. E. Holt· 3 shared R. R. Wick· 3 shared A. W. J. Jenney· 2 shared D. W. Spelman· 2 shared K. L. Wyres· 2 shared L. M. Judd· 2 shared M. Mirceta· 2 shared R. A. Strugnell· 2 shared

Activity by Year

2016-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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3 shared papersMicrobiology

K. E. Holt

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Author profile →

4 papers

Recent·Most cited

Bridging the gap between bioinformatics and the clinical and public health microbiology laboratory: An ISO-accredited genomics workflow for antimicrobial resistance

N. L. Sherry, K. Horan, S. A. Ballard, A. Goncalves da Silva, C. L. Gorrie, M. B. Schultz, K. Stevens, M. Valcanis, M. Sait, T. P. Stinear, B. P. Howden, T. Seemann

This paper develops and validates abritAMR, an ISO-accredited bioinformatics platform for detecting antimicrobial resistance genes with high accuracy and specificity.

bioRxiv · May 26, 2022 · PreprintMicrobiology

Distinct evolutionary dynamics of horizontal gene transfer in drug resistant and virulent clones of Klebsiella pneumoniae

K. L. Wyres, R. R. Wick, L. M. Judd, R. Froumine, A. Tokolyi, C. L. Gorrie, M. M. C. Lam, S. Duchene, A. Jenney, K. E. Holt

The paper compares the evolutionary dynamics of horizontal gene transfer in drug-resistant and virulent Klebsiella pneumoniae clones to assess the risk of gene convergence.

bioRxiv · Sep 12, 2018Microbiology

Antimicrobial resistant Klebsiella pneumoniae carriage and infection in specialized geriatric care wards linked to acquisition in the referring hospital

C. L. Gorrie, M. Mirceta, R. R. Wick, L. M. Judd, K. L. Wyres, N. R. Thomson, R. A. Strugnell, N. F. Pratt, J. F. Garlick, K. M. Watson, P. C. Hunter, S. A. McGloughlin, D. W. Spelman, A. W. J. Jenney, K. E. Holt

The paper investigates K. pneumoniae carriage and infection in geriatric wards, finding that most isolates originated from patients' gut microbiomes, while ESBL strains were acquired in the referring hospital.

bioRxiv · Nov 13, 2017Microbiology

Gastrointestinal carriage is a major reservoir of K. pneumoniae infection in intensive care patients

C. L. Gorrie, M. Mirceta, R. R. Wick, D. J. Edwards, R. A. Strugnell, N. Pratt, J. Garlick, K. Watson, D. Pilcher, S. McGloughlin, D. W. Spelman, A. W. J. Jenney, K. E. Holt

This study finds that gastrointestinal carriage of K. pneumoniae is a significant risk factor for infection in ICU patients, with half of infections originating from the patient's own microbiota.

bioRxiv · Dec 23, 2016Microbiology