RAS-induced transformation of mammary epithelial cells relies on ZEB1-dependent cellular reprogramming via a paracrine process
H. De Blander, L. Tonon, F. Fauvet, R. M. Pommier, C. Lamblot, R. Benhassoun, F. Angileri, B. Gibert, M. Ouzounova, A.-P. Morel, A. Puisieux
This study shows RAS-induced transformation of mammary epithelial cells depends on ZEB1-dependent reprogramming via a paracrine process involving senescent cell-derived cytokines.
bioRxiv · Jun 23, 2022 · PreprintCancer Biology