Impact of immediate cryopreservation on the establishment of patient derived xenografts from head and neck cancer patients.
L. Abel, A. Durmaz, R. Hu, C. Longhurst, A. M. Baschnagel, D. L. Wheeler, J. G. Scott, R. J. Kimple
This study shows that fresh human cancer tissue can be cryopreserved and later implanted to establish PDXs without affecting growth rates or histologic parameters, enabling molecular profiling before implantation.
bioRxiv · Feb 3, 2020Cancer Biology