L. Abel

Plasmodium falciparum genetic diversity in coincident human and mosquito hosts

The paper assesses genetic diversity of Plasmodium falciparum in human and mosquito hosts, finding higher diversity in mosquitoes than humans.

Human T-bet governs innate and innate-like adaptive IFN-γ immunity against mycobacteria

This study identifies T-bet deficiency as a cause of mycobacterial disease by impairing IFN-γ production in innate and innate-like adaptive lymphocytes.

Distinct antibody repertoires against endemic human coronaviruses in children and adults

The paper analyzes antibody repertoires against endemic human coronaviruses in children and adults, finding distinct epitope targets and cross-reactivity patterns.

Development and Characterization of Patient-Derived Xenografts from Non-Small Cell Lung Cancer Brain Metastases

This study establishes and characterizes patient-derived xenografts of NSCLC brain metastases, showing strong phenotypic and molecular correlation with original tumors and therapeutic response to targeted treatments.

Impact of immediate cryopreservation on the establishment of patient derived xenografts from head and neck cancer patients.

This study shows that fresh human cancer tissue can be cryopreserved and later implanted to establish PDXs without affecting growth rates or histologic parameters, enabling molecular profiling before implantation.

High syphilis seropositivity in European brown hares, Lower Saxony, Germany

The paper reports high seropositivity for Treponema paraluisleporidarum in European brown hares in Lower Saxony, Germany.

IRF4 haploinsufficiency in a family with Whipples disease

This study identifies IRF4 haploinsufficiency as the genetic cause of Whipples disease in a family, showing age-dependent incomplete penetrance and chronic Tw carriage preceding disease onset.