C. M. Branco

MICROVASCULAR ENDOTHELIAL CELL ADAPTATION TO HYPOXIA IS ORGAN-SPECIFIC AND CONDITIONED BY ENVIRONMENTAL OXYGEN

This study shows that microvascular endothelial cells (MVEC) respond to hypoxia differently depending on their organ of origin and environmental oxygen levels, with mitochondrial function playing a key role in their metabolic adaptation.

Circulating levels of epirubicin cause endothelial senescence while compromising metabolic activity and vascular function

This study shows that low doses of epirubicin cause endothelial senescence, reduced metabolic activity, and impaired vascular function in both cell and animal models.