MICROVASCULAR ENDOTHELIAL CELL ADAPTATION TO HYPOXIA IS ORGAN-SPECIFIC AND CONDITIONED BY ENVIRONMENTAL OXYGEN
M. Reiterer, A. J. Eakin, A. Burke, R. S. Johnson, C. M. Branco
This study shows that microvascular endothelial cells (MVEC) respond to hypoxia differently depending on their organ of origin and environmental oxygen levels, with mitochondrial function playing a key role in their metabolic adaptation.
bioRxiv · Aug 25, 2020Cell Biology