A dual-clock-driven model emulating the effects of either Ano1 or IP3R knock-out on lymphatic muscle cell pace-making
E. J. Hancock, S. D. Zawieja, C. Macaskill, M. J. Davis, C. D. Bertram
The paper develops a dual-clock model to simulate the effects of Ano1 or IP3R knock-out on lymphatic muscle cell pacemaking, improving accuracy by coupling M-clock and C-clock oscillators.
bioRxiv · Nov 6, 2022 · PreprintBiophysics