A broad-specificity O-glycoprotease that enables improved analysis of glycoproteins and glycopeptides containing intact complex O-glycans
S. Vainauskas, H. Guntz, E. McLeod, C. McClung, C. Ruse, X. Shi, C. H. Taron
This paper introduces IMPa, a broad-specificity O-glycoprotease that efficiently cleaves glycoproteins with sialylated and asialylated O-glycans, enabling improved O-glycoproteomics analysis.
bioRxiv · Sep 9, 2021Biochemistry