Probabilistic graph-based model uncovers previously unseen druggable vulnerabilities in major solid cancers
Y. Zhu, S. T. Schmidt, L. Zhao, C. Jiang, P. DI MICCO, C. Mitsopoulos, A. Futreal, B. Al-Lazikani
This paper introduces a graph-based model to identify druggable vulnerabilities in solid cancers, finding 43 novel targets by leveraging cooperativity in molecular networks.
bioRxiv · Jun 4, 2024 · PreprintCancer Biology