Crystal structure of human endothelin ETB receptor in complex with peptide inverse agonist IRL2500
C. Nagiri, W. Shihoya, A. Inoue, F. M. Ngako Kadji, J. Aoki, O. Nureki
The paper reports the crystal structure of the human ETB receptor complexed with the inverse agonist IRL2500, revealing its binding mechanism and ETB-selectivity.
bioRxiv · Nov 2, 2018Biochemistry