Alternative ergosterol biosynthetic pathways confer antifungal drug resistance in the human pathogens within the Mucor species complex
M. I. Navarro-Mendoza, C. Perez-Arques, J. Parker, Z. Xu, S. Kelly, J. Heitman
This study identifies Erg3 and Erg6a as key enzymes in the ergosterol biosynthetic pathway of Mucor circinelloides, showing their roles in antifungal drug resistance and virulence.
bioRxiv · Dec 1, 2023Microbiology