Spatially Resolved Transcriptomics Deconvolutes Histological Prognostic Subgroups in Patients with Colorectal Cancer and Synchronous Liver Metastases
C. S. Wood, K. Pennel, H. Leslie, A. Legrini, A. Cameron, L. Melissourgou-Syka, J. Quinn, H. Van Wyk, J. Hay, A. Roseweir, C. Nixon, C. Roxburgh, D. McMillan, A. Biankin, O. J. Sansom, , N. Jamieson
This study uses spatial transcriptomics to identify prognostic immune and stromal subgroups in colorectal cancer liver metastases, revealing distinct transcriptomic programs associated with survival outcomes.
bioRxiv · Sep 21, 2022 · PreprintCancer Biology