A polyglutamine domain is required for de novo CIZ1 assembly formation at the inactive X chromosome
S. Sofi, L. Williamson, G. L. Turvey, C. Scoynes, C. Hirst, J. Godwin, N. Brockdorff, J. Ainscough, D. Coverley
The paper shows that a polyglutamine domain in CIZ1 is required for forming de novo assemblies at the inactive X chromosome, mediated by interactions with Xist RNA.
bioRxiv · Nov 10, 2020Cell Biology