Dynamic tracing using ultra-bright labelling and multi-photon microscopy identifies endothelial uptake of poloxamer-188 coated poly(lactic-co-glycolic acid)nano-carriers in vivo
I. Khalin, C. Severi, D. Heimburger, A. Wehn, F. Hellal, A. Reisch, A. Klymchenko, N. Plesnila
The paper develops highly fluorescent PLGA nanoparticles coated with PF-68 and uses in vivo imaging to show their uptake by endothelial cells in the brain and peripheral organs.
bioRxiv · Nov 19, 2020Bioengineering