Prevalence and mechanisms of evolutionary contingency in human influenza H3N2 neuraminidase
R. Lei, T. J. C. Tan, A. H. Garcia, Y. Wang, C. Teo, G. Gopan, Z. Tavakoli Dargani, Q. W. Teo, C. S. Graham, S. K. Nair, N. C. Wu
The paper identifies deleterious mutations in human influenza H3N2 neuraminidase and reveals epistatic networks shaping its evolution.
bioRxiv · Feb 24, 2022Microbiology