Effects of tumor mutation burden on the antigen presentation pathway
E. M. Garcia-Rivera, J. Park, A. Desai, R. Boidot, S. Chevrier, C. Truntzer, F. Ghiringhelli, M. Borad, A. S. Mansfield
The paper examines how tumor mutation burden affects antigen presentation pathway genes and finds that APG mutations are linked to improved progression-free survival with PD-1 inhibitors.
bioRxiv · Apr 14, 2021 · PreprintImmunology