Rpgrip1l controls ciliary gating by ensuring the proper amount of Cep290 at the vertebrate transition zone
A. Wiegering, R. Dildrop, C. Vesque, S. Schneider-Maunoury, C. Gerhardt
This study identifies Rpgrip1l's role in regulating ciliary gating by maintaining Cep290 levels at the vertebrate transition zone and suggests eupatilin as a potential therapeutic agent for ciliopathies.
bioRxiv · Feb 10, 2020Cell Biology