Long-read sequencing identifies aberrant fragmentation patterns linked to elevated cell-free DNA levels in cancer
B. P. Berman, S. A. Erdman, C. Wheeler, J. Cayford, J.-V. Turatsinze, M. Ouzounova, M. Piecyk, M. Herzog, L. Payen-Gay, T. Walter, T. K. Kelly
The paper uses long-read sequencing to analyze cfDNA fragmentation patterns in cancer patients, identifying hypofragmentation and hyperfragmentation linked to elevated cfDNA levels.
bioRxiv · May 2, 2024Cancer Biology