Fragment Linker Prediction Using Deep Encoder-Decoder Network for PROTAC Drug Design
C.-T. Kao, C.-T. Lin, C.-L. Chao, C.-C. Lin
This paper introduces AIMLinker, a deep learning model that generates PROTACs analogs with improved chemical properties by integrating structural filters and molecular docking validation.
bioRxiv · Nov 17, 2022Pharmacology & Toxicology