Graded Hair Cell Ablation Reveals Functional Redundancy in the Mature Mouse Vestibular System
Tian Wang, Davood K. Hosseini, Ahmad Mahhoudi, Zahra N. Sayyid, Jun He, Caroline Sit, Zelma G. Iriarte Oporto, Hong Zhu, Wu Zhou, Alan Gi-Lun Cheng
This study shows that the adult mouse vestibular system maintains functional responses despite significant hair cell loss, with different levels of redundancy in macula and crista ampullaris.
bioRxiv · Nov 27, 2025 · PreprintNeuroscience