Mature and migratory dendritic cells promote immune infiltration and response to anti-PD-1 checkpoint blockade in metastatic melanoma
Jiekun Yang, Cassia Wang, Doris Fu, Li‐Lun Ho, Kyriakitsa Galani, Lee Chen, Jose Gonzalez, Jolene Yin Ling Fu, Amy Y. Huang, Dennie Tompers Frederick, Liang He, Mukta Asnani, Rahul Tacke, Emily J. Robitschek, Sandeep K. Yadav, , Manolis Kellis
The paper identifies a mature dendritic cell subtype associated with improved immune response and prognosis in melanoma patients treated with anti-PD-1 checkpoint inhibitors.
Nature Communications · Sep 1, 2025Peer-reviewedCancer Biology