Author

Changhui Deng

University of California, San FranciscoPrimary ORCID profile (0009-0007-7515-8995 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

Changhui DengiD1 paper · Hunan University

Biology Disciplines

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Bioinformatics· 1 Microbiology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:plant (other)· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Jiashun ZhengiD· 2 shared Aiming WangiD· 1 shared Asma Aziz· 1 shared Evan Wu· 1 shared Fangfang LiiD· 1 shared Hao LiiD· 1 shared Hao Li· 1 shared Hongguang CuiiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersSystems Biology

Jiashun ZhengORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A genetic switch involving EGR1 and EZH2 links aging and development across human tissues

Neha Khetan, Jiashun Zheng, Changhui Deng, Evan Wu, Hao Li

This paper identifies a genetic switch between EZH2 and EGR1 that connects aging and development across human tissues, showing its role in cellular state transitions and rejuvenation.

bioRxiv · Jul 30, 2026 · PreprintSystems Biology

Yeast aging from a dynamic systems perspective: Analysis of single cell trajectories reveals significant interplay between nuclear size scaling, proteasome dynamics, and mitochondrial morphology

Michael Mobaraki, Changhui Deng, Jiashun Zheng, Hao Li

The paper analyzes single-cell yeast aging trajectories to show proteasome dynamics and nuclear size scaling are key predictors of lifespan and influence mitochondrial morphology.

bioRxiv · Mar 11, 2025 · PreprintBioinformatics

A conserved lysine/arginine-rich motif in potyviral 6K1 protein is key in engaging autophagy-mediated self-degradation for completing pepper veinal mottle virus infection

Weiyao Hu, Changhui Deng, Qin Li, Peilan Liu, Linxi Wang, Xiaoqin Wang, Wei Shi, Asma Aziz, Fangfang Li, Xiaofei Cheng, Aiming Wang, Zhaoji Dai, Xiaohua Xiang, Hongguang Cui

This study identifies a conserved lysine/arginine-rich motif in potyviral 6K1 protein that mediates autophagy-mediated self-degradation, essential for viral infection.

Journal of Virology · Feb 10, 2025Peer-reviewedMicrobiology