Scalable expansion and hepatic zone maturation of hepatic progenitor cells from human pluripotent stem cells
Mina Ogawa, Jeff C. Liu, Abolfazl Dadvar, Britney Tian, Xinyuan Zhao, Ian Fernandes, Kentaro Minegishi, Kenichiro Takase, Changyi Cui, Marcela Hernandez, Yuichiro Higuchi, Hiroshi Suemizu, Ian D. McGilvray, Sonya A. MacParland, Gary D. Bader, Shinichiro Ogawa
This study develops a method to generate functional hepatocytes from human pluripotent stem cells through controlled differentiation and tissue engineering.
bioRxiv · Jun 13, 2025 · PreprintCell Biology