Author

Chao Chen

Central South University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Microbiology· 3 Bioinformatics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Research Focus:database / resource· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Benno KuropkaiD· 1 shared Bernhard LolliD· 1 shared Changjian LiuiD· 1 shared Chase L. BeiseliD· 1 shared Die Hong· 1 shared Dongning Yu· 1 shared Eberhard Klauck· 1 shared Fenghao Yuan· 1 shared

Activity by Year

2017-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 9 mutual co-author links

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1 shared paperMicrobiology

Benno KuropkaORCID

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5 papers

Recent·Most cited

A compact Druantia defense clears phage infections via single-stranded DNA recognition and directional duplex unwinding

Stephanie Himpich, Thomas Gaudin, Lena M. Grass, Huihui Li, Vu Van Loi, Chao Chen, Eberhard Klauck, Philipp F. Popp, Maximilian Feussner, Benno Kuropka, Tarek Hilal, Bernhard Loll, Marc Erhardt, Haike Antelmann, Chase L. Beisel, Markus C. Wahl

This paper describes how the Druantia type III-A defense system in E. coli clears phage infections by recognizing single-stranded DNA and unwinding DNA duplexes directionally.

Cell Reports · Sep 22, 2026Peer-reviewedMicrobiology

Human hindbrain organoids with segment-specific 5-HT neurons for motor modulation

Jinkui Zhu, Wei Pang, Yantong Liu, Yao Yin, Xiaoxiang Lu, Jianfeng Wei, Linlin Jiang, Wei Zhou, Yajing Cao, Qinzhi Zhang, Sisi Chen, Siyuan Chu, Zhaoxuan Ji, Die Hong, Yuanyuan Li, , 向阳飞

This study generates human hindbrain organoids with segment-specific 5-HT neurons to model serotonergic development and motor modulation, revealing DISC1 deficiency disrupts serotonergic development and motor function.

bioRxiv · May 29, 2026 · PreprintNeuroscience

Exploring the microbial community structure and metabolic gene clusters during silage fermentation of paper mulberry, and developing the high-protein woody plant as ruminant feed

Zhumei Du, Lin Sun, Chao Chen, Jing Lin, Fuyu Yang, Yimin Cai

The paper uses PacBio SMRT sequencing to analyze microbial communities and metabolic gene clusters in paper mulberry silage, showing shifts in bacterial dominance and identifying key metabolic pathways affecting fermentation quality.

Animal Feed Science and Technology · May 1, 2021Peer-reviewedMicrobiology

Insight into relationship between micro-consortia, nitrogen source and petroleum degradation at low temperature anaerobic condition

Jicheng Yu, Chao Chen, Changjian Liu, Dongning Yu, Shuai Chen, Fenghao Yuan, Yang Fu, Qiu Liu

This study investigates how different nitrogen sources affect anaerobic microbial consortia and petroleum degradation in marine sediments, finding that optimal nitrogen proportions enhance degradation.

bioRxiv · Jun 29, 2018 · PreprintMicrobiology

BGDMdocker: an workflow base on Docker for analysis and visualization pan-genome and biosynthetic gene clusters of bacterial

Gong Cheng, Quan Lu, Zongshan Zhou, Ling Ma, Guocai Zhang, WU Yilei, Chao Chen

The paper introduces BGDMdocker, a Docker-based workflow for analyzing and visualizing pan-genomes and biosynthetic gene clusters in bacteria, with results from 44 Bacillus amyloliquefaciens strains.

bioRxiv · Feb 3, 2017 · PreprintBioinformatics