NeurosciencebioRxivPreprint
Hampered AMPK-ULK1 cascade in Alzheimer disease (AD) instigates mitochondria dysfunctions and AD-related alterations that are alleviated by metformin
Arnaud Mary, Samantha Barale, Fanny Eysert…·Mounia Chami
This study shows that impairing the AMPK-ULK1 cascade in Alzheimer's disease leads to mitochondrial dysfunction and AD-related changes, which are improved by metformin treatment.