Fanny Eysert

This paper develops a microfluidic co-culture model to study microglial synapse phagocytosis in AD, finding that APP microglia show enhanced synaptic uptake under inflammation.

This study characterizes large extracellular vesicles containing mitochondria (EVMs) from Alzheimer's Disease cells, showing they carry pathological mitochondrial dysfunction and spread it to recipient cells.

This study shows that impairing the AMPK-ULK1 cascade in Alzheimer's disease leads to mitochondrial dysfunction and AD-related changes, which are improved by metformin treatment.

The paper examines mitochondrial alterations in fibroblasts from Alzheimer's disease patients and links them to clinical hallmarks and cognitive decline.

The paper identifies FERMT2 as a key modulator of axon guidance and synaptic plasticity in an APP-dependent manner, linking its genetic risk variant to Alzheimer's disease through miRNA regulation.

The paper develops a microfluidic co-culture model to study Aβ1-42-induced synaptotoxicity and shows Pyk2 overexpression in postsynaptic neurons protects against it.