Author

Chen Tang

The University of Texas Southwestern Medical Center

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Biology Disciplines

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Bioinformatics· 1

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Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Approach:graph neural network· 1 Research Focus:spatial domain detection· 1 Assay:spatial transcriptomics· 1 Research Focus:trajectory inference· 1

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Guanghua XiaoiD· 1 shared Lei DongiD· 1 shared Lei Yu· 1 shared Lori XuiD· 1 shared Q. Y. LiiD· 1 shared Xue XiaoiD· 1 shared Yuansheng ZhouiD· 1 shared

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2026-2026 · peak 1/yr

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Guanghua XiaoORCID

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1 paper

Recent·Most cited

3D reconstruction of spatial transcriptomics with spatial pattern enhanced graph convolutional neural network

Chen Tang, Yuansheng Zhou, Xue Xiao, Lei Dong, Lei Yu, Q. Y. Li, Guanghua Xiao, Lori Xu

This paper introduces Spa3D, a method that reconstructs 3D spatial structures from 2D spatial transcriptomics data, improving spatial domain identification, cell-cell communication analysis, and developmental trajectory modeling.

Briefings in Bioinformatics · Jan 1, 2026Peer-reviewedBioinformatics