Shieldin and CST co-orchestrate DNA polymerase-dependent tailed-end joining reactions independently of 53BP1-governed repair pathway choice
Ashleigh King, Pia I. Reichl, Jean Metson, Robert Parker, Daniella Munro, Catarina Oliveira, Lucia Sommerová, Jordan R. Becker, Daniel Biggs, Chris Preece, Benjamin Davies, J. Ross Chapman
This study investigates the role of shieldin and CST in DNA end-joining and HR suppression, showing their collaboration in DNA repair and the independence of 53BP1's effects.
Nature Structural & Molecular Biology · Sep 3, 2024Peer-reviewedMolecular Biology