Evidence for phospholipid export from the gram-negative inner membrane: time to rethink the Mla pathway?
Gareth W. Hughes, Stephen C. L. Hall, Claire S. Laxton, Pooja Sridhar, Amirul H. Mahadi, Caitlin Hatton, Thomas J. Piggot, Mohammed Jamshad, Vaclav Spana, Cadby T. Ian, Christopher Harding, Georgia L. Isom, Jack Bryant, Rebecca J. Parr, Yasin Yakub, , Timothy J. Knowles
The paper solves the crystal structure of MlaC and shows the Mla pathway exports phospholipids from the inner membrane to the periplasm, challenging the previous belief in retrograde transport.
bioRxiv · Aug 9, 2018 · PreprintBiophysics